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|ProName:||BK||Chemical Formula:||C11H13NO3||Purity:||99%min||Application:||Pharmaceutical Intermediate||CAS:||186028-79-5||Appearance:||Crystals||High Light:||
active pharmaceutical ingredients,
bulk pharmaceutical chemicals
BKEBDP BKMMDA Ethylone Bkmdea Molly Research Chemical CAS NO 186028-79-5 High Purity
Proname: bkedpb, bkmdea BK md ma
CAS : 186028-79-5
Formula : C11H13NO3
Molecular weight: 249.310
Purity: > 99.7%
Application: Intermediate for organic syntheses
Package: Aluminum foil bag
Transportation: PostNL,EMS, Fedex, DHL
Storage: Dry and cool
Delivery time: Within 24 hours
Port : HK
"Methylone" is also a trademarked brand name for an injectable form of methylprednisolone, a corticosteroid hormone used to treat arthritis and severe allergic reactions; hence, methylone may be confused with it. Aside from context, they can be distinguished by the fact that the name will usually be capitalized when referring to the prescription drug.
A proposed alternate name is bk-MDMC, or beta-keto-MDMC. While this nomenclature has not caught on because the name "methylone" became widely used before the conflicting Methylone trademark was noticed, the analogous names for related chemicals bk-MDEA and bk-MBDB have become the established names for those substances.
Methylone acts as a mixed reuptake inhibitor/releasing agent of serotonin, norepinephrine, and dopamine.
In comparison to MDME, it has approximately 3x lower affinity for the serotonin transporter, while its affinity for the norepinephrine and dopamine transporters is similar.
Notably, methylone's affinity for the vesicular monoamine transporter 2 (VMAT2) is about 13x lower than that of MDME.
The results of these differences in pharmacology relative to MDME are that methylone is less potent in terms of dose, has more balanced catecholaminergic effects relative to serotonergic, and behaves more like a reuptake inhibitor like methylphenidate than a releaser like amphetamine;however, methylone has relatively robust releasing capabilities,perhaps due to its ability to phosphorylate the monoamine transporters being similar in potency relative to MDMC.
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